The most important number when comparing South Carolina health insurance is the annual ceiling on what you'll pay when you're sick. Ambetter has the lowest of any carrier in the state's 2026 marketplace, which is why it's the best choice for most South Carolina residents.
In practice, the annual ceiling limits how much you could end up paying when you need surgery or have a health emergency. Blue Cross Blue Shield costs $14 less per month but its Silver deductible is $852 above Ambetter's at $4,064. The monthly savings takes more than five years to offset that deductible difference.
First Choice Next is the stronger pick if you use care more than a few times a year. Its deductible is $1,022 lower than Ambetter's, so your insurer starts paying earlier on every visit. Blue Cross Blue Shield is the pick if you need coverage for doctors outside your insurer's approved provider list. No other South Carolina carrier in 2026 provides that option, which is why it appears on this list despite carrying the highest Silver deductible in the state.











